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varicocele
The relationship of varicocele with hormones has been evidenced by studies conducted. Detrimental effects of varicocele include Leydig cell (the cells that produce testosterone) dysfunctions, impaired tubular structure, interstitial fibrosis and reduced sperm production. Leydig cell dysfunction might result in reduced testosterone levels. A study conducted show that intratesticular testosterone level must be minimum 20 ng/dl for healthy continuance of sperm production. The same study has found that intratesticular testosterone level is significantly lower in varicocele patients.
Effects of varicocele on testicles and sperm
In presence of varicocele, testicle volume might decrease or testicles might shrink abnormally, depending on the severity of varicocele
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